Mikrobiol. Z. 2015; 77(5):87-94. Ukrainian.
doi: https://doi.org/10.15407/microbiolj77.05.087

Definition of Women Reproductive Tract Microflora Composition
Using Test-System “Femoflor-17”

Sklyar T.V.1, Krysenko O.V.1, Voronkova O.S.1, Papiashvili M.G.2, Vinnikov A.I.1

1Oles Gonchar Dnipropetrovsk National University

2Independent laboratory INVITRO

The data about composition of the vaginal microflora of women with use of the test system “Femoflor-17” was analyzed. Established that 92.7 % of samples contained lactobacilli. For quantitaty of lactobacilli vaginal flora characterized as normobiosis. The dysbiosis in the background detection of mycoplasma, ureaplasma and yeast of genus Candida identified for 38.2 % of the samples. Mycoplasma, ureaplasma and candida as monoinfection detected in 71 % of cases and as an association of two pathogens in 29 % of cases.
In establishing compliance obtained by the test system “Femoflor-17” results to clinical and bacteriological markers of vaginal dysbiosis characterized as moderate anaerobic dysbiosis - 6 % of the samples, moderate aerobic dysbiosis - 10 %, moderate anaerobic-aerobic dysbiosis - 35 %, pronounced anaerobic dysbiosis - 12 % of the samples, expressed aerobic dysbiosis - 10%, anaerobic-aerobic expressed dysbiosis - 27% of the samples. Showing dominance of obligate anaerobic microorganisms associations among other microorganisms.

Key words: reproductive tract microflora, Femoflor-17, opportunistic and pathogenic bacteria.

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  1. Ankirskaya A.S. Bakterialnyi vaginoz. Akusherstvo i gine­kologiya. 2005; 3:10-13.
  2. Voronin K.V., Chuyko V.I., Nakhla B.S. Bakterialnyi vaginoz beremennykh: problemy i resheniya. Klinichna meditsina. 2011; 16(4):1-9.
  3. Gordeeva G.D., Kogan B.G. Ekosistema vlagalishcha i vaginalnye infektsii. Zdorove zhenshchiny. 2008; 3(35):70-74.
  4. Dmitriev G.A., Glazko I.I. Bakterialnyi vaginoz. Moscow: Izd-vo Binom, 2008.
  5. Nikitenko I.N. Rol anaerobnoy uslovno-patogennoy flory v razvitii vospa­litelnykh zabolevaniy mochepolovogo trakta. Dermatologiya ta venerologiya. 2002; 3:19-23.
  6. Nosenko O.M., Ostapenko O.I., Rutynska H.V. Metod diahnostyky bakterialnoho vahinozu v zhinok reproduk­tyvnoho viku za dopomohoyu kompleksnoi kilkisnoi polimeraznoi lantsyuhovoi re­aktsii v rezhymi realnoho chasu z vykorystannyam test-naboriv «Femoflor-16». Medyko-sotsialni problemy sim'yi. 2010; 15(4):43-55.
  7. Ob unifikatsii mikrobiologicheskikh (bakteriologicheskikh) metodov issledovaniya, primenyaemykh v kliniko-diagnosticheskikh laboratoriyakh lechebno-profilakticheskikh uchrezhdeniy: prikaz 535. Vid 22.04.1985r. Moscow: MOZ SSSR, 1985.
  8. Pysaryeva S.P., Vorobyova I.I., Mohilyevska S.I.Rol henitalnykh infektsiy u vynyknenni akusherskykh ta perynatalnykh uskladnen. Zdorove zhenshchyny. 2010; 4:158-160.
  9. Primenenie metoda polimeraznoy tsepnoy reaktsii v realnom vremeni dlya otsen­ki mikrobiotsenoza urogenitalnogo trakta u zhenshchin (test Femoflor). Moscow, 2011.
  10. Bodnaryuk O.I., Andriyets O.A., Sakriyer A.L. ta in. Rol bakterialnoho vahinozu v rozvytku zapalnykh zakhvoryuvan orhaniv malo­ho taza u divchat-pidlitkiv. Bukovynskyi medychnyi visnyk. 2011; 15(1):17-19.
  11. Simoes J.A., Discacciati M.G., Brolazo E.M. et al. Clinical diagnosis of bacterial vaginosis. Int. J. Gynaecol. Obstet. 2006; 94(1):28-32. https://doi.org/10.1016/j.ijgo.2006.04.013