Mikrobiol. Z. 2015; 77(1):26-32. Ukrainian.
doi: https://doi.org/10.15407/microbiolj77.01.026

The Influence of Synthetic Derivatives of Porphyrins and Fluorene and Surfactants
on Activity and Biosynthesis of Bacillus subtilis 147 α-Amylase

Аvdiyuk К.V.1, Varbanets L.D.1, Philippova T.O.2, Zhilina Z.I.2, Ishkov Yu.V.2, Karpenko E.V.3, Shulga A.N.3

1Zabolotny Institute of Microbiology and Virology, NAS of Ukraine
154 Akad. Zabolotny Str., Kyiv, 03143, Ukraine

2Odessa Mechnikov National University

3Lviv Department of Litvinenko Institute of Physico-Organic Chemistry and Coal Chemistry, NAS of Ukraine

For the first time the effect of certain synthetic derivatives of porphyrins and fluorene and surfactants on the biosynthesis and α-amylase activity of Bacillus subtilis 147 was studied. It is shown that the test compounds inhibited the both activity and biosynthesis of the enzyme. Only germanium complex of mesotetraphenylporphyrin chloride at a concentration of 0,01%, and zinc complex of meso-tetraphenyl porphyrin at a concentration of 0,1% did not affect on the synthesis and activity of B. subtilis 147 α-amylase, respectively.

Key words: α-аmylase, Bacillus subtilis, synthetic porfirine and fluorene derivatives, surfactants.

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